Coming Soon: Essential Open Source Software for Science – Chan Zuckerberg Initiative

The Chan Zuckerberg Initiative will soon invite applications for open source software projects that are essential to biomedical research. Applicants can request funding between $50k and $250k for one year. This RFA is the first of a series. CZI will invite applications during three distinct cycles, with rounds beginning June 18, 2019; mid-December 2019; and mid-June 2020. Read our Medium post to learn more….”

Power to the Protocols! – Chan Zuckerberg Science Initiative – Medium

“We require our grantees to contribute to open science in several ways, including:

  • Depositing software code to an open repository such as GitHub;
  • Submitting results to open-access preprint servers like bioRxiv upon submission to a peer-reviewed journal, if not earlier;
  • Making experimental protocols openly accessible….”

These challenges helped us identify a new technology platform for developing and sharing protocols. is an open access resource that allows researchers to discover and share up-to-date science methods, similar to the way code can be shared on GitHub. …”

Plan U: A proposal to achieve universal access to scientific and medical research via funder preprint mandates

“If all research funders required their grantees to post their manuscripts first on preprint servers — an approach we refer to as “Plan U” — the widespread desire to provide immediate free access to the world’s scientific output would be achieved with minimal effort and expense. As noted above, mathematicians, physicists and computer scientists have been relying on arXiv as their primary means of communication for decades. The biomedical sciences were slower to adopt preprinting, but bioRxiv is undergoing exponential growth and several million readers access articles on bioRxiv every month. Depositing preprints is thus increasingly common among scientists, and mandating it would simply accelerate adoption of a process many predict will become universal in the near future.

There is a precedent for mandating preprint deposition: since 2017, the Chan Zuckerberg Initiative (CZI) has mandated that all grantees deposit preprints prior to or at submission for formal publication. This requirement has been accepted by CZI-funded investigators, many of whom were already routinely depositing manuscripts on bioRxiv….”

Mark Zuckerberg’s man in the lab: ‘I want science to happen faster’ | Science | The Guardian

An interview with neuroscientist Jeremy Freeman, manager of computational biology at the Chan Zuckerberg Initiative (CZI). Quoting Freeman: “We [at CZI] are absolutely committed to open dissemination of data and code and knowledge; that’s something I have been committed to all the time I’ve been a scientist.”