As the end of the year draws in, PLOS ONE Staff Editors put together a list of some their favourite papers from 2019. Behavioral and Social Sciences, Neuroscience, Mental Health In an archaeological investigation, Ehud
Category Archives: Regeneration
First issue of Regeneration is now available online!
Wiley is delighted to announce the launch and publication of the inaugural first issue of one of its newest open access journals, Regeneration. The journal is the first, world-class publication of its kind dedicated to the rapidly expanding field of regeneration and repair.
Regeneration aims to become the journal of choice for those looking to publish top quality, original research related to regeneration and repair in its many forms, and in all relevant animal and plant species.
Read Editor-in-Chief Susan Bryant’s inaugural editorial here.
Read the first published articles here:
Experimentally induced metamorphosis in axolotls reduces regenerative rate and fidelity James R. Monaghan, Adrian C. Stier, François Michonneau, Matthew D. Smith, Bret Pasch, Malcolm Maden and Ashley W. Seifert
Salamanders regenerate limbs throughout life, but it is unclear how body size, aging, or metamorphosis affects regeneration. Here, we show that metamorphosis has a negative impact on limb regeneration rate and fidelity by limiting cell proliferation in metamorphic limbs.
Regeneration of reptilian scales after wounding: neogenesis, regional difference, and molecular modules Ping Wu, Lorenzo Alibardi and Cheng-Ming Chuong
Reptile scale development and regeneration occur through different processes. A–D, embryonic reptile scales develop from a flat bilayer epidermis to symmetric scale anlagen to asymmetric scale anlagen and further to mature scales. E–H, skin regenerates scales from flat wound epidermis to peg formation to elongating pegs and further to differentiating pegs. Despite these differences, they share similarities in proliferation patterns, epithelial–mesenchymal interactions and molecular modules.
Position-specific induction of ectopic limbs in non-regenerating blastemas on axolotl forelimbs Catherine McCusker, Jeffrey Lehrberg and David Gardiner
To test the hypothesis that retinoid acid (RA) reprograms the positional information in limb blastemas cells to a singular posterior-ventral-proximal (PVPr) identity, we treated blastemas at different positions on the limb circumference to determine whether ectopic limbs formed. We observed that RA treatment of blastemas in anterior and dorsal locations, but not posterior and ventral locations, resulted in the induction of complete ectopic limbs. These findings are consistent with the hypothesis that RA treatment reprograms the information in blastema cells to the PVPr position on the limb, and demonstrate that RA can be used to induce a regenerative response in anterior and dorsally located non-regenerative wounds.
We would like to invite you to submit your research paper to Regeneration at www.regenerationjournal.com. All authors retain copyright on their articles and all articles are fully open access upon publication.
First issue of Regeneration is now available online!
Wiley is delighted to announce the launch and publication of the inaugural first issue of one of its newest open access journals, Regeneration. The journal is the first, world-class publication of its kind dedicated to the rapidly expanding field of regeneration and repair.
Regeneration aims to become the journal of choice for those looking to publish top quality, original research related to regeneration and repair in its many forms, and in all relevant animal and plant species.
Read Editor-in-Chief Susan Bryant’s inaugural editorial here.
Read the first published articles here:
Experimentally induced metamorphosis in axolotls reduces regenerative rate and fidelity James R. Monaghan, Adrian C. Stier, François Michonneau, Matthew D. Smith, Bret Pasch, Malcolm Maden and Ashley W. Seifert
Salamanders regenerate limbs throughout life, but it is unclear how body size, aging, or metamorphosis affects regeneration. Here, we show that metamorphosis has a negative impact on limb regeneration rate and fidelity by limiting cell proliferation in metamorphic limbs.
Regeneration of reptilian scales after wounding: neogenesis, regional difference, and molecular modules Ping Wu, Lorenzo Alibardi and Cheng-Ming Chuong
Reptile scale development and regeneration occur through different processes. A–D, embryonic reptile scales develop from a flat bilayer epidermis to symmetric scale anlagen to asymmetric scale anlagen and further to mature scales. E–H, skin regenerates scales from flat wound epidermis to peg formation to elongating pegs and further to differentiating pegs. Despite these differences, they share similarities in proliferation patterns, epithelial–mesenchymal interactions and molecular modules.
Position-specific induction of ectopic limbs in non-regenerating blastemas on axolotl forelimbs Catherine McCusker, Jeffrey Lehrberg and David Gardiner
To test the hypothesis that retinoid acid (RA) reprograms the positional information in limb blastemas cells to a singular posterior-ventral-proximal (PVPr) identity, we treated blastemas at different positions on the limb circumference to determine whether ectopic limbs formed. We observed that RA treatment of blastemas in anterior and dorsal locations, but not posterior and ventral locations, resulted in the induction of complete ectopic limbs. These findings are consistent with the hypothesis that RA treatment reprograms the information in blastema cells to the PVPr position on the limb, and demonstrate that RA can be used to induce a regenerative response in anterior and dorsally located non-regenerative wounds.
We would like to invite you to submit your research paper to Regeneration at www.regenerationjournal.com. All authors retain copyright on their articles and all articles are fully open access upon publication.
Wiley Launches New Journal – Regeneration
Wiley is thrilled to announce the launch of a new open access journal solely dedicated to regeneration and repair together with a team of high profile international editors – Regeneration. Regeneration is a peer-reviewed, open access journal dedicated to the publication of papers covering regeneration and tissue repair in animals and plants.
Against the backdrop of basic research in developmental biology, and in conjunction with the ascendancy of stem cell biology, the time is ripe to explore the next frontier: natural and assisted healing and regeneration. The goal of the editors and publishers of Regeneration is to provide the first dedicated venue for research related to repair and regeneration in its many forms, and in all relevant species.
With an aging population in the Western world, a growing need for replacing organs is irrevocable, which has put emphasis on the need of increasing and enhancing research in regeneration and repair. Funding to the field has increased in recent years in most countries to further improve and grow the research and it is our hope that Regeneration will be instrumental in communicating these vital results to the community in the future.
The journal’s Editor-in-Chief is Susan V. Bryant, Research Professor and Associate Vice Chancellor for Research in the Department of Developmental and Cell Biology, University of California, Irvine. Susan is supported by a diverse and internationally prominent Editorial Board of established scientists who have devoted their careers to regeneration and repair.
The journal will publish articles under the Creative Commons Attribution (CC BY) License, allowing authors to comply with Open Access Mandates. Authors are invited to submit articles via the journal’s online submission site, or ask the editorial office for more information about whether their article is suitable for this new journal.
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