1 – Results from a malaria indicator survey highlight the importance of routine data capture in high-risk forest and farm transmission sites in Vietnam to tailor location-specific malaria elimination interventions

In this survey, Ngo and co-workers assess the knowledge about malaria and preventative measures in mobile human populations sleeping and working in forests or on farms in Vietnam. The survey highlights the importance of monitoring remote high-risk transmission areas to effectively tailor malaria interventions.

2 – Cross-reactive inhibitory antibody and memory B cell responses to variant strains of Duffy Binding Protein II at post-Plasmodium vivax infection

Thawornpan and co-workers investigate the cross reactivity of antibodies against the Plasmodium vivax Duffy binding protein (DBP), a potential vaccine candidate. The authors investigate the immune response against DBP in mice, thus providing valuable insights for future design strategies for effective vaccines against Plasmodium vivax.

3 – Cross-sectional Survey of Asymptomatic Malaria in Dak Nong Province in the Central Highlands of Vietnam for the Malaria Elimination Roadmap

Quang and colleagues investigate the prevalence of asymptomatic malaria in people living in three communes in Vietnam. The research highlights asymptomatic parasite carriers as undetected reservoirs for future malaria transmissions. This study concludes that knowledge about the prevalence and distribution of asymptomatic malaria will benefit future elimination efforts. 

4 – Study protocol for development of an options assessment toolkit (OAT) for national malaria programs in Asia Pacific to determine best combinations of vivax radical cure for their given contexts 

To enable the most effective strategies for combating malaria caused by Plasmodium vivax in the Asia Pacific region, Manash Shrestha and co-workers are planning to identify various factors that determine the unique context of different transmission environments. Based on these factors, the help of experts will be employed to develop an adaptable tool kit that will help decision-makers to tailor their anti-malaria approaches.

5 – A systematic review and meta-analysis of asymptomatic malaria infection in pregnant women in Sub-Saharan Africa: a challenge for malaria elimination efforts

This systematic review by Yonas Yimam and colleagues finds evidence in the existing literature that asymptomatic malaria infections, predominantly caused by P. falciparum, can cause anemia in pregnant women. The authors conclude that antenatal care should be adapted to take into consideration the possible effect of asymptomatic malaria infections on pregnant women in Sub-Saharan Africa.

Non-destructive imaging and spectroscopic techniques were used to authenticate coins depicting an obscure ‘Roman emperor’ named Sponsian. These coins were thought to be forgeries. The authentication forces a re-evaluation of Sponsian as a historical figure. Combining evidence from the coins with the historical record, the study proposes that Sponsian ruled the isolated Roman Province of Dacia during the military crisis of the 260s CE.

This large survey by Gopalakrishna and colleagues of researchers in the Netherlands revealed the prevalence of questionable research practices and suggests ways to promote research integrity. It suggests that greater emphasis on scientific norm subscription, strengthening reviewers in their role as gatekeepers of research quality and curbing the “publish or perish” incentive system promotes research integrity.

In western cultures, emotions induced by music are strongly influenced by ‘major’ and ‘minor’ characteristics in harmonics, but is is unknown whether this effect exists universally. The authors examined whether non-Western cultures experience these typical emotive shifts in music in a sample of participants living in a remote region of Papua New Guinea with differing levels of exposure to Western-influenced music. The findings showed that emotive valence of major and minor was strongly associated with exposure to Western-influenced music and culture, indicating that culture is a strong mediator of people’s emotional responses to music. The study was also only one of a very few number of studies in this literature to study these effects in a non-industrialized context where participants have little exposure to a globalized music culture.

There is evidence of race- and gender-based discrimination in the publishing industry. One possible explanation is the preferences of book consumers. Weinberg and Kapelner tested this hypothesis with a large-scale experiment in which they collected ratings of mocked-up books from over 9000 participants who were presented with book covers and descriptions from both fiction and non-fiction genres, with one of three possible titles per book randomly assigned. Race, gender, and age of the author were signaled via names and photographs. The authors found no support for any claim of consumer bias against black or females authors. In fact, participants were willing to pay approximately $0.50 more for books by Black writers. The authors conclude that there is no evidence of taste-based preferences by consumers that would rationalize the historic discriminatory treatment of Black or of female authors by publishers nor of discrimination based on an author’s age.

Individuals with mental health problems often face discrimination. Here, Beaton and colleagues analyse free text comments from adults with attention deficit hyperactivity disorder (ADHD) on their experiences of criticism from family, friends and colleagues. Participants reported commonly criticised behaviours and traits, with many noting they felt consistently criticised and felt unable to succeed. The authors indicate that the findings highlight the importance of advocating for a more flexible society that is accepting of individuality and neurodiversity.

In an effort to establish the use of single-nucleus RNA-sequencing to detect local changes in gene expression for early Drosophila embryos, Albright and colleagues compared nuclei transcript abundance differences between wide type and dCTCF mutants and identified distinct clusters that corresponded to spatial regions of the embryo. A resource of candidate differentially expressed genes was provided to explore the subtle changes upon loss of dCTCF gene. The results highlighted the potential of this new technique as a means of understanding the regulation of gene expression in the early Drosophila embryo.

The development of efficient and early COVID-19 testing methods is a very timely subject and much work remains to advance from proofs of concepts to practical applications. In this popular article, Grandjean and colleagues conducted a double-blinded test of COVID-19 detection using trained dogs and suggest that the detection of COVID-19 by dogs could be an alternative to antigenic tests.

Alquezar and colleagues present the first feather hydrogen isoscape for Brazil. Isoscapes are essentially isotopic maps that model how isotopes vary in space and time. As such, isoscapes can be used in a variety of applications in order to understand animal origins, for instance within ecology and forensic sciences. The Brazil hydrogen isoscape was developed through collection of feathers from ornithological collections and field campaigns in National Parks around the country, focusing on tanager species belonging to the family Thraupidae. These data were analysed in conjunction with climatic variables, such as temperature, precipitation and solar radiation, using machine learning in order to build a map of feather isotopes across Brazil. Although the model has limitations, including relatively low predictive power for this first iteration, isoscapes like these are increasingly deployable within forensic investigations, such as the illegal wildlife trade.

Synthetic opiod fentanyl and its analogues have widespread use in anesthesia and pain management, but despite being highly controlled substances, their illicit use and unpredictable fatal dosage when combined with other substances have led to tragic consequences in many countries. This new method reported by Carlos A. Valdez and colleagues is effective at detecting fentanyl and acetylfentanyl at levels reflecting those reported in overdose victims, and the chemical reaction approach used in the method enables the detection and identification of unknown fentanyls, with potential implications for diagnosis and monitoring supply.

Kay and colleagues from The University of Toronto present a proof-of-concept method of tuning liquid droplet morphology. They do this by creating a modified version of a Hele-Shaw cell and allowing the boundary valves to be either open or closed to the atmosphere. This allows for control of the pressure, which means that droplet shape and position can be manipulated using the local flow fields. B adding a dye to the liquid, in this case carbon black to castor oil, they created droplet morphologies that can be switched between being optically transmissible and absorptive. This sort of liquid smart material can potentially be employed in a variety of applications, such as shading, camouflage and dynamic displays.

Artificial intelligence and deep learning approaches hold promise to revolutionize medical practice, including the assessment and selection of the most viable embryos for vitro fertilization (IVF). In this paper, Berntsen and colleagues developed a deep learning-based embryo selection model based on time-lapse microscopy images. They showed that their fully automated model performed better than state-of-the-art, manually annotated methods. In addition, using a large dataset from 18 IVF clinics, they showed that the model is generalizable across different subgroups of age and clinical conditions, and correlated with traditional embryo development and morphology parameters. This model will help establish efficient, reliable, and reproducible tools in IVF clinics to combat rising infertility rates worldwide.

Stress is an inevitable aspect of daily life, and it’s essential to find ways to manage it. One form of stress-relief that has been studied is social touch, such as massages. However, the impact of other forms of physical touch on stress have not been widely explored in literature . This study looked at the impact of a short-term embrace between romantic partners on stress levels. The results showed that women who embraced their partner before a stressful situation had a lower cortisol response compared to a control group. No similar stress-reducing effects were observed in men. The study suggests that a short-term embrace before a stressful situation can help reduce stress in women.

The Zika virus (ZIKV) infects humans via sexual contact or mosquito bites and presents a significant threat to newborns of mothers infected with the virus during pregnancy. In this article, Agudelo and Ventresca establish a mathematical model that analyzes the impact of the sexual and mosquito transmission on ZIKV spread within a population. They concluded that ZIKV spreads mostly via mosquito transmission, while sexual transmission alone appears negligible for viral dissemination. The model can serve as a powerful tool in combating viral spread by providing reliable information for the implementation of protective health policies.

Evidence supports multiple health benefits of physical activity for cancer survivors, however, many cancer survivors are not sufficiently active to achieve these benefits. In this study protocol, Liao and colleagues describe a randomized pilot study to test the feasibility of a physical activity intervention in 50 cancer survivors. The novel intervention will demonstrate the immediate positive impact of physical activity to participants through the use of wearable devices. The authors hypothesize that “biofeedback” from wearable devices may help to motivate behavioral change.

TikTok is a popular social media platform amongst young people. Use of this platform for fitness and nutrition advice is very popular, however the quality of this content has not been well researched. This study investigated key themes in posts related to nutrition and weight-related content on this platform. From 1000 videos, each with over a billion views, the majority of posts were found to present weight-normative views, which may negatively impact young viewers with body image/eating disorders. This study indicates the importance of helping TikTok users discern credible information, and the ability to selectively remove triggering content from their feeds, which may help address the prevalence of weight-normative content and its potentially negative impact.

Conducting the first experience sampling study on the emotional outcomes of hunger, Swami and colleagues investigated the relationship between hunger and negative emotions, known to many as feeling “hangry”. The findings showed that greater levels of self-reported hunger were associated with greater feelings of anger and irritability, suggesting that feeling “hangry” is a real experience. The results of the study might facilitate the understanding of everyday experiences of emotions, support practitioners in ensuring productive individual behaviours and interpersonal relationships and could potentially help individuals to regulate certain emotions by putting feelings into words and labelling an emotion.