Abstract: This program supports the creation of a prototype Open Knowledge Network — an interconnected network of knowledge graphs supporting a very broad range of application domains. Open access to shared information is essential for the development and evolution of artificial intelligence (AI) and AI-powered solutions needed to address the complex challenges facing the nation and the world. Knowledge graphs, which represent relationships among real-world entities, provide a powerful approach for organizing, representing, integrating, reusing, and accessing data from multiple structured and unstructured sources using ontologies and ontology alignment. Currently, private-sector investments in knowledge graphs power numerous consumer applications including web search, e-commerce, banking, drug discovery, advertising, etc. Undertaking a similar but inclusive, open, and community-driven effort and making use of publicly available data holds the potential to create a platform that would empower government and non-government users — fueling evidence-based policymaking, continued strong economic growth, game-changing scientific breakthroughs, while addressing complex societal challenges from climate change to social equity.