The journal brings together articles on a range of oncology specialties, covering cancer biology, clinical cancer research and cancer prevention, with authors from across the globe.
Below are some top articles which Editor-in-Chief Prof. Qingyi Wei has highlighted from the issue. We hope that you enjoy this exciting new content.
Prognostic impact and the relevance of PTEN copy number alterations in patients with advanced colorectal cancer (CRC) receiving bevacizumab
Timothy J. Price, Jennifer E. Hardingham, Chee K. Lee, Amanda R. Townsend, Joseph W. Wrin, Kate Wilson, Andrew Weickhardt, Robert J. Simes, Carmel Murone and Niall C. Tebbutt
Summary: Phosphatase and tensin homologue (PTEN) remains controversial as a predictive and prognostic marker. There also remains uncertainty as to the best method to assess PTEN status. Here, we use PTEN copy number and assess the association of outcome and PTEN loss, as defined by copy number variation.
A contemporary analysis of morbidity and outcomes in cytoreduction/hyperthermic intraperitoneal chemoperfusion
Michelle Haslinger, Valerie Francescutti, Kristopher Attwood, Judith Andrea McCart, Marwan Fakih, John M. Kane III and Joseph J. Skitzki
Summary: In the contemporary setting, cytoreductive surgery and hyperthermic intraperitoneal chemotherapy (CS/HIPEC) are associated with a low mortality and improved survival. When present, complications are associated with a decreased overall survival. This treatment modality should be considered within the context of multidisciplinary care for select peritoneal carcinomatosis patients.
Comparison of the accuracy of Hybrid Capture II and polymerase chain reaction in detecting clinically important cervical dysplasia: a systematic review and meta-analysis
Hung N. Luu, Kristina R. Dahlstrom, Patricia Dolan Mullen, Helena M. VonVille and Michael E. Scheurer
Summary: The selection of a screening test is important to detect clinically relevant cases of Human papillomavirus (HPV) infection while avoiding the unnecessary cost, stress and compromise of the cervix to patients associated with over-treating mild cytological abnormalities. Given the clinical relevance and importance of cervical cancer worldwide, our results support the use of Hybrid Capture II (HCII) in cervical screening programs.
Cancer Medicine is a peer reviewed, interdisciplinary journal providing rapid publication of cutting-edge research from global biomedical researchers across the cancer sciences.