Wiley is delighted to announce the launch and publication of the inaugural first issue of one of its newest open access journals, Regeneration. The journal is the first, world-class publication of its kind dedicated to the rapidly expanding field of regeneration and repair.
Regeneration aims to become the journal of choice for those looking to publish top quality, original research related to regeneration and repair in its many forms, and in all relevant animal and plant species.
Read Editor-in-Chief Susan Bryant’s inaugural editorial here.
Read the first published articles here:
Experimentally induced metamorphosis in axolotls reduces regenerative rate and fidelity James R. Monaghan, Adrian C. Stier, François Michonneau, Matthew D. Smith, Bret Pasch, Malcolm Maden and Ashley W. Seifert
Salamanders regenerate limbs throughout life, but it is unclear how body size, aging, or metamorphosis affects regeneration. Here, we show that metamorphosis has a negative impact on limb regeneration rate and fidelity by limiting cell proliferation in metamorphic limbs.
Regeneration of reptilian scales after wounding: neogenesis, regional difference, and molecular modules Ping Wu, Lorenzo Alibardi and Cheng-Ming Chuong
Reptile scale development and regeneration occur through different processes. A–D, embryonic reptile scales develop from a flat bilayer epidermis to symmetric scale anlagen to asymmetric scale anlagen and further to mature scales. E–H, skin regenerates scales from flat wound epidermis to peg formation to elongating pegs and further to differentiating pegs. Despite these differences, they share similarities in proliferation patterns, epithelial–mesenchymal interactions and molecular modules.
Position-specific induction of ectopic limbs in non-regenerating blastemas on axolotl forelimbs Catherine McCusker, Jeffrey Lehrberg and David Gardiner
To test the hypothesis that retinoid acid (RA) reprograms the positional information in limb blastemas cells to a singular posterior-ventral-proximal (PVPr) identity, we treated blastemas at different positions on the limb circumference to determine whether ectopic limbs formed. We observed that RA treatment of blastemas in anterior and dorsal locations, but not posterior and ventral locations, resulted in the induction of complete ectopic limbs. These findings are consistent with the hypothesis that RA treatment reprograms the information in blastema cells to the PVPr position on the limb, and demonstrate that RA can be used to induce a regenerative response in anterior and dorsally located non-regenerative wounds.
We would like to invite you to submit your research paper to Regeneration at www.regenerationjournal.com. All authors retain copyright on their articles and all articles are fully open access upon publication.
