Working with citizens to reflect on solutions to society’s challenges. This is the path that science is treading today with increasing vigour, including in healthcare. In conjunction with the regional consortium TOPFIT Citizenlab, the University of Twente (UT) is focusing on improving citizens’ years of happiness and health with the help of technology. Parallel to this, the Citizen Science Hub was launched in Twente on 20 November 2020. In 2021, such hubs will follow in at least three other locations in Europe within the INCENTIVE project. Iedereen Wetenschapper invited UT experts Sabine Wildevuur, director of DesignLab at University of Twente, and Renske van Wijk, project leader of TOPFIT Citizenlab, for a Q&A session.